Jaskaran B Singh Selected Research

Treatment-Resistant Depressive Disorder

1/2023	Adverse Events and Measurement of Dissociation After the First Dose of Esketamine in Patients With TRD.
1/2022	Relationship Between Dissociation and Antidepressant Effects of Esketamine Nasal Spray in Patients With Treatment-Resistant Depression.
1/2022	Comparison of Long-Term Efficacy and Safety of Esketamine Nasal Spray Plus Oral Antidepressant in Younger Versus Older Patients With Treatment-Resistant Depression: Post-Hoc Analysis of SUSTAIN-2, a Long-Term Open-Label Phase 3 Safety and Efficacy Study.
11/2021	The effect of esketamine in patients with treatment-resistant depression with and without comorbid anxiety symptoms or disorder.
12/2020	Effects of Mu-Opiate Receptor Gene Polymorphism rs1799971 (A118G) on the Antidepressant and Dissociation Responses in Esketamine Nasal Spray Clinical Trials.
1/2020	Approval of esketamine for treatment-resistant depression.
1/2020	Efficacy and Safety of Esketamine Nasal Spray Plus an Oral Antidepressant in Elderly Patients With Treatment-Resistant Depression-TRANSFORM-3.
1/2020	Cardiac Safety of Esketamine Nasal Spray in Treatment-Resistant Depression: Results from the Clinical Development Program.
1/2020	Esketamine Nasal Spray Plus Oral Antidepressant in Patients With Treatment-Resistant Depression: Assessment of Long-Term Safety in a Phase 3, Open-Label Study (SUSTAIN-2).
1/2020	Managing Esketamine Treatment Frequency Toward Successful Outcomes: Analysis of Phase 3 Data.

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Jaskaran B Singh Research Topics

Disease

18	Treatment-Resistant Depressive Disorder 01/2023 - 01/2016
4	Major Depressive Disorder (Major Depressive Disorders) 05/2024 - 01/2006
4	Nausea 10/2019 - 01/2016
4	Headache (Headaches) 10/2019 - 01/2016
4	Dizziness (Lightheadedness) 10/2019 - 01/2018
4	Bipolar Disorder (Manic Depressive Psychosis) 05/2011 - 02/2005
3	Vertigo (Positional Vertigo) 10/2019 - 01/2019
2	Dysgeusia (Parageusia) 01/2019 - 01/2019
2	Mood Disorders (Mood Disorder) 06/2013 - 01/2006
1	Psychotic Disorders (Schizoaffective Disorder) 01/2023
1	Hypertension (High Blood Pressure) 01/2020
1	Tachycardia (Tachyarrhythmias) 01/2020
1	Sleepiness 01/2019
1	Ectopic Pregnancy 01/2018
1	Syncope (Fainting) 01/2018
1	Body Weight (Weight, Body) 08/2016
1	Mania (Manias) 09/2007
1	Disruptive, Impulse Control, and Conduct Disorders (Kleptomania) 12/2006
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 12/2006
1	Feeding and Eating Disorders (Eating Disorder) 12/2006
1	Anxiety Disorders (Anxiety Disorder) 12/2006
1	Alcoholism (Alcohol Abuse) 12/2006
1	Substance-Related Disorders (Drug Abuse) 12/2006

Drug/Important Bio-Agent (IBA)

18	Antidepressive Agents (Antidepressants)IBA 01/2023 - 02/2005
17	EsketamineIBA 01/2023 - 01/2016
10	Nasal SpraysIBA 01/2022 - 01/2019
2	N-Methylaspartate (NMDA)IBA 08/2016 - 01/2006
2	Ketamine FDA LinkGeneric 08/2016 - 06/2013
2	LithiumIBA 12/2006 - 02/2005
1	AcidsIBA 05/2024
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 05/2024
1	Antihypertensive Agents (Antihypertensives)IBA 01/2020
1	Excitatory Amino Acid AntagonistsIBA 08/2016
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 06/2013
1	Biomarkers (Surrogate Marker)IBA 06/2013
1	Dopamine Agonists (Dopamine Agonist)IBA 05/2011
1	Pramipexole (Mirapex)FDA LinkGeneric 05/2011
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 05/2011
1	Tamoxifen FDA LinkGeneric 09/2007
1	Antimanic AgentsIBA 09/2007
1	Protein Kinase CIBA 09/2007
1	Antipsychotic Agents (Antipsychotics)IBA 12/2006
1	Anticonvulsants (Antiepileptic Drugs)IBA 12/2006
1	Memantine (Namenda)FDA Link 01/2006
1	Riluzole FDA LinkGeneric 02/2005
1	Glutamic Acid (Glutamate)FDA Link 02/2005

Therapy/Procedure

2	Secondary Prevention 01/2020 - 01/2019
2	Therapeutics 01/2018 - 01/2006
1	Intravenous Administration 08/2016
1	Deep Brain Stimulation 01/2006
1	Vagus Nerve Stimulation 01/2006